853 research outputs found

    Performance Analysis of Indoor Optical Wireless Links

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    Indoor wireless optical communication is a good alternative to existing mature RF technology. However various challenges in indoor optical wireless technology are due to free space loss, ambient light, and multi path dispersion causing inter symbol interference (ISI). The degradation in performance due to these facts is very much influenced by the channel topology. So in this paper the performance of indoor optical configuration has been analyzed using three types of channel topologies viz., directed (LOS), non-directed (LOS), and multi beam diffused link for various transmitter and receiver design parameters. The analysis has been carried using Optiwave simulation tools

    Identification of insertion hot spots for non-LTR retrotransposons: computational and biochemical application to entamoeba histolytica

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    The genome of the human pathogen Entamoeba histolytica contains non-long terminal repeat (LTR) retrotransposons, the EhLINEs and EhSINEs, which lack targeted insertion. We investigated the importance of local DNA structure, and sequence preference of the element-encoded endonuclease (EN) in selecting target sites for retrotransposon insertion. Pre-insertion loci were tested computationally to detect unique features based on DNA structure, thermodynamic considerations and protein interaction measures. Target sites could readily be distinguished from other genomic sites based on these criteria. The contribution of the EhLINE1-encoded EN in target site selection was investigated biochemically. The sequence-specificity of the EN was tested in vitro with a variety of mutated substrates. It was possible to assign a consensus sequence, 5'-GCATT-3', which was efficiently nicked between A-T and T-T. The upstream G residue enhanced EN activity, possibly serving to limit retrotransposition in the A+T-rich E.histolytica genome. Mutated substrates with poor EN activity showed structural differences compared with normal substrates. Analysis of retrotransposon insertion sites from a variety of organisms showed that, in general, regions of favorable DNA structure were recognized for retrotransposition. A combination of favorable DNA structure and preferred EN nicking sequence in the vicinity of this structure may determine the genomic hotspots for retrotransposition

    Definition of the on-time delivery indicator in rapid software development

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    Rapid software development (RSD) is an approach for developing software in rapid iterations. One of the critical success factors of an RSD project is to deliver the product releases on time and with the planned features. In this paper, we elaborate an exploratory definition of the On-Time Delivery strategic indicator in RSD based on the literature and interviews with four companies. This indicator supports decision-makers to detect development problems in order to avoid delays and to estimate the additional time needed when requirements, and specifically quality requirements, are considered.Peer ReviewedPostprint (author's final draft

    Neonatal, 1–59 month, and under-5 mortality in 597 Indian districts, 2001 to 2012: estimates from national demographic and mortality surveys

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    Background India has the largest number of child deaths of any country in the world, and has wide local variation in under-5 mortality. Worldwide achievement of the UN 2015 Millennium Development Goal for under-5 mortality (MDG 4) will depend on progress in the subregions of India. We aimed to estimate neonatal, 1–59 months, and overall under-5 mortality by sex for 597 Indian districts and to assess whether India is on track to achieve MDG 4. Methods We divided the 2012 UN sex-specifi c birth and mortality totals for India into state totals using relative birth rates and mortality from recent demographic surveys of 24 million people, and divided state totals into totals for the 597 districts using 3 million birth histories. We then split the results into neonatal mortality and 1–59 month mortality using data for 109 000 deaths in children younger than 5 years from six national surveys. We compared results with the 2001 census for each district. Findings Under-5 mortality fell at a mean rate of 3·7% (IQR 3·2–4·9) per year between 2001 and 2012. 222 (37%) of 597 districts are on track to achieve the MDG 4 of 38 deaths in children younger than 5 years per 1000 livebirths by 2015, but an equal number (222 [37%]) will achieve MDG 4 only after 2020. These 222 lagging districts are home to 41% of India’s livebirths and 56% of all deaths in children younger than 5 years. More districts lag behind the relevant goal for neonatal mortality (251 [42%]) than for 1–59 month mortality (197 [33%]). Just 81 (14%) districts account for 37% of deaths in children younger than 5 years nationally. Female mortality at ages 1–59 months exceeded male mortality by 25% in 303 districts in nearly all states of India, totalling about 74 000 excess deaths in girls. Interpretation At current rates of progress, MDG 4 will be met by India around 2020—by the richer states around 2015 and by the poorer states around 2023. Accelerated progress to reduce mortality during the neonatal period and at ages 1–59 months is needed in most Indian districts. Funding Disease Control Priorities 3, Canadian Institutes of Health Research, International Development Research Centre, US National Institutes of Health

    Adding interventions to mass measles vaccinations in India.

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    OBJECTIVE: To quantify the impact on mortality of offering a hypothetical set of technically feasible, high-impact interventions for maternal and child survival during India's 2010-2013 measles supplementary immunization activity. METHODS: We developed Lives Saved Tool models for 12 Indian states participating in the supplementary immunization, based on state- and sex-specific data on mortality from India's Million Deaths Study and on health services coverage from Indian household surveys. Potential add-on interventions were identified through a literature review and expert consultations. We quantified the number of lives saved for a campaign offering measles vaccine alone versus a campaign offering measles vaccine with six add-on interventions (nutritional screening and complementary feeding for children, vitamin A and zinc supplementation for children, multiple micronutrient and calcium supplementation in pregnancy, and free distribution of insecticide-treated bednets). FINDINGS: The measles vaccination campaign saved an estimated 19 016 lives of children younger than 5 years. A hypothetical campaign including measles vaccine with add-on interventions was projected to save around 73 900 lives (range: 70 200-79 300), preventing 73 700 child deaths (range: 70 000-79 000) and 300 maternal deaths (range: 200-400). The most effective interventions in the whole package were insecticide-treated bednets, measles vaccine and preventive zinc supplementation. Girls accounted for 66% of expected lives saved (12 712/19 346) for the measles vaccine campaign, and 62% of lives saved (45 721/74 367) for the hypothetical campaign including add-on interventions. CONCLUSION: In India, a measles vaccination campaign including feasible, high-impact interventions could substantially increase the number of lives saved and mitigate gender-related inequities in child mortality

    Age-specifi c and sex-specifi c adult mortality risk in India in 2014: analysis of 0·27 million nationally surveyed deaths and demographic estimates from 597 districts

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    Background As child mortality decreases rapidly worldwide, premature adult mortality is becoming an increasingly important contributor to global mortality. Any possible worldwide reduction of premature adult mortality before the age of 70 years will depend on progress in India. Indian districts increasingly have responsibility for implementing public health programmes. We aimed to assess age-specifi c and sex-specifi c adult mortality risks in India at the district level. Methods We analysed data from fi ve national surveys of 0∙27 million adult deaths at an age of 15–69 years together with 2014 demographic data to estimate age-specifi c and sex-specifi c adult mortality risks for 597 districts. Cause of death data were drawn from the verbal autopsies in the Registrar General of India’s ongoing Million Death Study. Findings In 2014, about two-fi fths of India’s men aged 15–69 years lived in the 253 districts where the conditional probability of a man dying at these ages exceeded 50%, and more than a third of India’s women aged 15–69 years lived in the 222 districts where the conditional probability of a woman dying exceeded 40%. The probabilities of a man or woman dying by the age of 70 years in high-mortality districts was 62% and 54%, respectively, whereas the probability of a man or woman dying by the age of 70 years in low-mortality districts was 40% and 30%, respectively. The roughly 10-year survival gap between high-mortality and low-mortality districts was nearly as extreme as the survival gap between the entire Indian population and people living in high-income countries. Adult mortality risks at ages 15–69 years was highest in east India and lowest in west India, by contrast with the north–south divide for child mortality. Vascular disease, tuberculosis, malaria and other infections, and respiratory diseases accounted for about 60% of the absolute gap in adult mortality risk at ages 15–69 years between high-mortality and low-mortality districts. Most of the variation in adult mortality could not be explained by known determinants or risk factors for premature mortality. Interpretation India’s large variation in adult mortality by district, notably the higher death rates in eastern India, requires further aetiological research, particularly to explore whether high levels of adult mortality risks from infections and non-communicable diseases are a result of historical childhood malnutrition and infection. Such research can be complemented by an expanded coverage of known eff ective interventions to reduce adult mortality, especially in high-mortality district

    Measuring and improving Agile Processes in a small-size software development company

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    Context: Agile software development has become commonplace in software development companies due to the numerous benefits it provides. However, conducting Agile projects is demanding in Small and Medium Enterprises (SMEs), because projects start and end quickly, but still have to fulfil customers' quality requirements. Objective: This paper aims at reporting a practical experience on the use of metrics related to the software development process as a means supporting SMEs in the development of software following an Agile methodology. Method: We followed Action-Research principles in a Polish small-size software development company. We developed and executed a study protocol suited to the needs of the company, using a pilot case. Results: A catalogue of Agile development process metrics practically validated in the context of a small-size software development company, adopted by the company in their Agile projects. Conclusions: Practitioners may adopt these metrics in their Agile projects, especially if working in an SME, and customise them to their own needs and tools. Academics may use the findings as a baseline for new research work, including new empirical studies.The authors would like to thank all the members of the QRapids H2020 project consortium.Peer ReviewedPostprint (published version

    Rock Mechanics challenges of depillaring at deep cover

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    Underground coal mining at deeper cover encounters difficult underground environment due to increase in gas content and rise in temperature transition of a mining practice from shallow to high depth cover encounters a big change in the rock mass characteristics and the stress condition becomes more complex. At higher depth of cover, the excavation starts encountering stress control regime rather than structural control behavior of the rock mass. Mechanisation and automation of underground mining activities is a solution to improve the performance of deeper mines but the approach should match with the rock mass and stress conditions of the site. Since inception, CIMFR (formerly, CMRI) is continuously working to understand behavior of the rock mass through laboratory testing, field investigations and study on simulated models. Obtained experiences during these investigations are observed to be of strategic importance during application of a modern technology to improve practical mining conditions. This paper reviews rock mechanics aspects of different mechanized pillar extraction approaches during mining of a deep seated coal seam and, also attempts to present an appraisal of some of the recent technical developments to overcome the challenges of a deep underground coal mining

    Continuously assessing and improving software quality with software analytics tools: a case study

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    In the last decade, modern data analytics technologies have enabled the creation of software analytics tools offering real-time visualization of various aspects related to software development and usage. These tools seem to be particularly attractive for companies doing agile software development. However, the information provided by the available tools is neither aggregated nor connected to higher quality goals. At the same time, assessing and improving software quality has also been a key target for the software engineering community, yielding several proposals for standards and software quality models. Integrating such quality models into software analytics tools could close the gap by providing the connection to higher quality goals. This study aims at understanding whether the integration of quality models into software analytics tools provides understandable, reliable, useful, and relevant information at the right level of detail about the quality of a process or product, and whether practitioners intend to use it. Over the course of more than one year, the four companies involved in this case study deployed such a tool to assess and improve software quality in several projects. We used standardized measurement instruments to elicit the perception of 22 practitioners regarding their use of the tool. We complemented the findings with debriefing sessions held at the companies. In addition, we discussed challenges and lessons learned with four practitioners leading the use of the tool. Quantitative and qualitative analyses provided positive results; i.e., the practitioners’ perception with regard to the tool’s understandability, reliability, usefulness, and relevance was positive. Individual statements support the statistical findings and constructive feedback can be used for future improvements. We conclude that potential for future adoption of quality models within software analytics tools definitely exists and encourage other practitioners to use the presented seven challenges and seven lessons learned and adopt them in their companies.Peer ReviewedPostprint (published version
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